Mark A Doll Selected Research

Acetyltransferases

1/2020	Acetylator Genotype-Dependent Dyslipidemia in Rats Congenic for N-Acetyltransferase 2.
1/2017	Congenic rats with higher arylamine N-acetyltransferase 2 activity exhibit greater carcinogen-induced mammary tumor susceptibility independent of carcinogen metabolism.
2/2011	No association between variant N-acetyltransferase genes, cigarette smoking and Prostate Cancer susceptibility among men of African descent.
12/2009	Differences between human slow N-acetyltransferase 2 alleles in levels of 4-aminobiphenyl-induced DNA adducts and mutations.
11/2009	N-acetyltransferase 2 genotype modification of active cigarette smoking on breast cancer risk among hispanic and non-hispanic white women.
2/2008	Meat intake, heterocyclic amine exposure, and metabolizing enzyme polymorphisms in relation to colorectal polyp risk.
10/2007	Tissue expression and genomic sequences of rat N-acetyltransferases rNat1, rNat2, rNat3, and Functional characterization of a novel rNat3*2 genetic variant.
8/2007	Functional characterization of single-nucleotide polymorphisms and haplotypes of human N-acetyltransferase 2.
7/2007	2-Amino-3,8-dimethylimidazo-[4,5-f]quinoxaline-induced DNA adduct formation and mutagenesis in DNA repair-deficient Chinese hamster ovary cells expressing human cytochrome P4501A1 and rapid or slow acetylator N-acetyltransferase 2.
5/2007	Identification of N-acetyltransferase 2 (NAT2) transcription start sites and quantitation of NAT2-specific mRNA in human tissues.

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Mark A Doll Research Topics

Disease

38	Neoplasms (Cancer) 01/2022 - 01/2002
17	Breast Neoplasms (Breast Cancer) 01/2022 - 07/2003
8	Acute Kidney Injury (Acute Renal Failure) 01/2022 - 02/2016
6	Inflammation (Inflammations) 01/2022 - 12/2003
5	Carcinogenesis 01/2020 - 09/2006
4	Fibrosis (Cirrhosis) 01/2022 - 03/2016
4	Urinary Bladder Neoplasms (Bladder Cancer) 01/2021 - 04/2011
3	Neoplasm Metastasis (Metastasis) 01/2022 - 01/2019
3	Prostatic Neoplasms (Prostate Cancer) 02/2011 - 01/2002
3	Adenocarcinoma 06/2008 - 07/2004
3	Pancreatic Neoplasms (Pancreatic Cancer) 06/2008 - 01/2006
2	Body Weight (Weight, Body) 01/2022 - 12/2003
2	DNA Repair-Deficiency Disorders (Chromosome Instability Syndromes) 01/2022 - 07/2007
2	Adenocarcinoma of Lung 08/2020 - 02/2016
2	Lung Neoplasms (Lung Cancer) 08/2020 - 10/2010
2	Chronic Renal Insufficiency 01/2018 - 03/2016
2	Hepatocellular Carcinoma (Hepatoma) 06/2015 - 07/2006
2	Colorectal Neoplasms (Colorectal Cancer) 01/2008 - 05/2007
2	Drug-Related Side Effects and Adverse Reactions 05/2007 - 01/2005
2	Necrosis 01/2006 - 12/2003
2	Hepatitis 01/2006 - 12/2003
1	Infections 01/2022
1	Non-alcoholic Fatty Liver Disease 01/2021
1	Dyslipidemias (Dyslipidemia) 01/2020
1	Insulin Resistance 01/2020
1	Essential Hypertension 12/2017
1	Bacterial Pneumonia 06/2017
1	Trypanosomiasis 02/2016
1	Wounds and Injuries (Trauma) 05/2014

Drug/Important Bio-Agent (IBA)

24	N-acetyltransferase 1IBA 01/2022 - 01/2002
21	CarcinogensIBA 01/2022 - 01/2002
18	AcetyltransferasesIBA 01/2020 - 01/2002
10	AminesIBA 01/2022 - 01/2002
9	Pharmaceutical PreparationsIBA 01/2022 - 11/2004
9	Cisplatin (Platino)FDA LinkGeneric 01/2022 - 02/2016
8	EnzymesIBA 01/2022 - 01/2006
5	Estrogen ReceptorsIBA 01/2022 - 06/2015
4	4-biphenylamineIBA 01/2022 - 02/2018
4	SmokeIBA 01/2021 - 07/2003
4	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 03/2005
3	Neutral CeramidaseIBA 01/2022 - 01/2021
3	Proteins (Proteins, Gene)FDA Link 08/2020 - 09/2004
3	Small Interfering RNA (siRNA)IBA 08/2020 - 01/2018
3	Arylamine N-AcetyltransferaseIBA 01/2017 - 04/2011
3	Superoxide DismutaseIBA 10/2010 - 03/2005
3	Cytochrome P-450 CYP1A2 (CYP1A2)IBA 06/2008 - 01/2006
3	CytochromesIBA 06/2008 - 01/2006
2	Messenger RNA (mRNA)IBA 01/2018 - 07/2006
2	N-acetyltalosaminuronic acid (NAT)IBA 05/2012 - 06/2008
2	Glutathione Transferase (Glutathione S-Transferase)IBA 12/2011 - 07/2003
2	QuinoxalinesIBA 07/2007 - 09/2006
2	Alanine Transaminase (SGPT)IBA 01/2006 - 09/2004
2	Reactive Oxygen Species (Oxygen Radicals)IBA 12/2004 - 12/2003
1	Chloroquine (Aralen)FDA LinkGeneric 01/2022
1	InterferonsIBA 01/2022
1	3-methyladenineIBA 01/2022
1	alizarinIBA 01/2022
1	SphingomyelinsIBA 01/2022
1	Histone Deacetylase InhibitorsIBA 01/2022
1	theasinensin AIBA 01/2022
1	sirtinolIBA 01/2022
1	SirtuinsIBA 01/2022
1	Cytochrome P-450 CYP1A1 (CYP1A1)IBA 01/2022
1	Monounsaturated Fatty AcidsIBA 01/2021
1	Biological ProductsIBA 01/2021
1	RNA (Ribonucleic Acid)IBA 01/2021
1	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 08/2020
1	LipidsIBA 01/2020
1	2-aminofluoreneIBA 01/2020
1	oxidized low density lipoproteinIBA 01/2020
1	Triglycerides (Triacylglycerol)IBA 01/2020
1	Glucose (Dextrose)FDA LinkGeneric 01/2020
1	Acetyl Coenzyme A (Acetyl-CoA)IBA 01/2019
1	AgarIBA 01/2019
1	Phenobarbital (Luminal)FDA Link 01/2018
1	Estradiol (Delestrogen)FDA LinkGeneric 01/2018
1	Perilipin-1IBA 01/2018
1	Biomarkers (Surrogate Marker)IBA 01/2018
1	Dithiothreitol (Cleland's Reagent)IBA 01/2018
1	Dihydrotestosterone (Androstanolone)IBA 01/2018
1	Hydralazine (Apresoline)FDA LinkGeneric 12/2017
1	MacrolidesIBA 06/2017
1	Anti-Bacterial Agents (Antibiotics)IBA 06/2017
1	solithromycinIBA 06/2017
1	Glucosylceramides (Glucocerebrosides)IBA 01/2017
1	Methylnitrosourea (N-Methyl-N-nitrosourea)IBA 01/2017
1	CeramidesIBA 01/2017
1	9,10-Dimethyl-1,2-benzanthraceneIBA 01/2017
1	ceramide glucosyltransferaseIBA 01/2017
1	Fibronectins (Fibronectin)IBA 03/2016
1	Transforming Growth Factors (Transforming Growth Factor)IBA 03/2016
1	Suramin (Suramin Sodium)IBA 02/2016
1	Dehydroepiandrosterone (DHEA)IBA 06/2015
1	GTP-Binding Proteins (G-Protein)IBA 06/2015
1	ErbB Receptors (EGF Receptor)IBA 05/2014
1	BetacellulinIBA 05/2014
1	LigandsIBA 05/2014
1	Coloring Agents (Dyes)IBA 12/2011
1	Hair DyesIBA 12/2011

Therapy/Procedure

1	Therapeutics 12/2017